THE PURSER WELLNESS ENCYCLOPEDIA

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Gene referenceSep 23, 2026

COMT

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Makes an enzyme that helps break down catechol compounds, including some neurotransmitters. A common variant does not by itself explain mood, attention or stress tolerance.

Gene referenceSep 23, 2026

GGH

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GGH encodes gamma-glutamyl hydrolase, which removes glutamate residues from folate compounds. This affects folate handling and helps explain why folate metabolism includes retention and processing as well as intake.

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