L-Methionine
Some search terms matchedAn amino acid used in protein synthesis and other metabolic processes.
Also called: Methionine
Where the cycle begins
Methionine is an essential amino acid used to make proteins. It also enters a pathway involving SAM, SAH, and homocysteine…
Vitamin B9 (Folate)
Some search terms matchedSupports DNA synthesis and one-carbon metabolism, including the pathway that processes homocysteine.
Also called: Vitamin B9 (Folate), Folate, B9, folic acid, methylfolate, 5-MTHF, folinic acid, foods high in folate
Different folate forms, …
ADIPOQ
Some search terms matchedADIPOQ encodes adiponectin, a hormone released by fat tissue that participates in insulin sensitivity and fat metabolism. Its name often appears in discussions of triglycerides, body composition and metabolic health.
Also called: Adiponecti…
APOE
Some search terms matchedAPOE encodes a protein that carries lipids between cells. The familiar APOE e2, e3 and e4 groupings depend on the combination of rs429358 and rs7412, not on either marker read in isolation.
Also called: Apolipoprotein E
Lipid transport and …
BHMT
Some search terms matchedBHMT helps recycle homocysteine into methionine using betaine. It is a different route from the folate and B12 pathway.
Also called: BHMT08, Betaine-Homocysteine S-Methyltransferase
Another route through the homocysteine map
BHMT is part of…
CD14
Some search terms matchedCD14 helps immune cells recognize microbial components, including bacterial lipopolysaccharide, as part of innate immune signaling. This places it upstream of some cytokine responses.
Also called: Cluster of Differentiation 14
How immune ce…
COL5A1
Some search terms matchedCOL5A1 encodes one component of type V collagen, which helps organize collagen fibers. It connects to the strength and structure of tendons, skin and other connective tissues.
Also called: Collagen Type V Alpha 1 Chain
Collagen structure, t…
FOLR2
Some search terms matchedFOLR2 encodes folate receptor beta, a folate-binding protein expressed in particular cell types, including subsets of immune cells. It is distinct from the FOLR1 receptor and the SLC19A1 reduced folate carrier.
Also called: Folate Receptor …
G6PC2
Some search terms matchedG6PC2 encodes a glucose-6-phosphatase-related protein expressed in pancreatic islet cells. Common variation is associated with differences in fasting glucose regulation; it is not the insulin receptor.
Also called: Glucose-6-Phosphatase Cat…
GAD1
Some search terms matchedGAD1 helps your body make GABA, a chemical messenger, from glutamate.
Also called: Glutamate Decarboxylase 1
The glutamate-to-GABA connection
Dr. Purser’s course uses GAD/GABA teaching to explain a connection between excitatory and inhibito…
GSR
Some search terms matchedGSR encodes glutathione reductase. It uses reducing power from NADPH to help convert oxidized glutathione back to reduced glutathione, allowing this antioxidant system to be reused.
Also called: Glutathione Reductase
Recycling used glutathi…
GSTM1
Some search terms matchedGSTM1 helps your body use glutathione to process some compounds.
Also called: Glutathione S-Transferase Mu 1
Using glutathione in conjugation
GSTM1 belongs to the glutathione transferase family. These enzymes use glutathione in conjugation …
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