Let’s explore “Genetics, CMA and blood tests”

GSR encodes glutathione reductase. It uses reducing power from NADPH to help convert oxidized glutathione back to reduced glutathione, allowing this antioxidant system to be reused.

GSTM1 helps your body use glutathione to process some compounds.

GSTP1 helps your body use glutathione to process some compounds.

GSTT1 helps your body use glutathione to process some compounds.

HDC is the gene name for Histidine Decarboxylase. Learn what a specific result could mean and what to ask about it.

HLA-DQA1 contributes to an HLA-DQ protein that presents antigen fragments to CD4 T cells. HLA-DQ function depends on pairing with an HLA-DQB chain, so an isolated marker is not a complete HLA type.

HLA-DQA2 is part of the HLA class II region involved in immune recognition. It should not be treated as interchangeable with HLA-DQA1 or as a measurement of how well the immune system fights infections.

IL21 encodes a cytokine involved in regulating lymphocytes, including B-cell responses. It sits within an immune network that connects T-cell help, antibody responses and inflammatory activity.

IL23R encodes part of the receptor that receives IL-23 signals. This connects the gene to the maintenance of Th17-related immune responses, which differ from the Th2 patterns discussed in allergy.

MAOA helps break down some chemical messengers. A gene result cannot predict a mood or behavior.

MAOB encodes monoamine oxidase B, an enzyme involved in breaking down monoamine compounds, including dopamine. It does not simply build dopamine, and a DNA marker is not a neurotransmitter measurement.

MMP3 encodes matrix metalloproteinase 3, an enzyme involved in breaking down components of the extracellular matrix. Controlled remodeling is part of repair, while excess activity can accompany inflammatory tissue damage.