Let’s explore “Hailey-Hailey disease & cytokines”

…ot the same as demonstrating prevention of every associated disease. How immune signals may connect In Dr. Purser’s model, homocysteine may relate to how cells respond to inflammation. He discusses genes, nutrients, antioxidant status, and …

…son is overlapping recruitment signals rather than a unique disease prediction from one marker. Closely related genes and nearby variants need careful naming and mapping. A question to bring to your visit Has the exact chemokine gene been i…

… a receptor. Their variants do not diagnose an inflammatory disease or select an immune-targeting drug. A question to bring to your visit What diagnosed condition or clinical finding makes the IL-23/Th17 pathway relevant here? Variant IDs i…

…ts this receptor pathway with celiac and inflammatory bowel disease contexts. A gene for receiving a signal is distinct from the gene that produces it. Symptoms and standard diagnostic testing should determine whether a gut inflammatory dis…

…ection, not evidence that a person with rs917997 has celiac disease or cannot regulate inflammation. Interpret symptoms and relevant testing before drawing a clinical conclusion. A question to bring to your visit What evidence beyond the ge…

…tance, and inflammatory responses in the liver. Fatty liver disease can progress to inflammation and scarring in some people. Follow the pathway Dr. Purser discusses hepatic stellate cells, fibrosis, and the interaction of cytokines with r…

…athway helps support Th17 immune cells and their downstream cytokines, including IL-17. Follow the pathway Dr. Purser connects IL-23 receptor signaling with inflammatory bowel disease, psoriasis, and inflammatory joint pathways. Targeting …

PURSER WELLNESSMTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors Miss From the reading room

…homocysteine, and a body-wide amplification of inflammatory cytokines. Homocysteine is not merely a cardiovascular marker. It is a potent “cytokine amplifier.” When levels climb above 10–12 µmol/L (my functional optimum is <7–8 µmol/L), hom…

…hione. Why does this matter? Because CF isn’t just a mucus disease — it’s an inflammatory cytokine storm driven by IL-8, IL-4, IL-5, and IL-13. Our research shows that restoring glutathione levels can calm these cytokines, reduce inflammat…

…te to conditions like skin inflammation, inflammatory bowel disease, and chronic pain. ✨ Reduces Pro-Inflammatory Cytokines By inhibiting cytokines like TNF-Alpha, SOD 3 can help soothe inflammation at its source. ✨ Supports Healthy Joint…

…te to conditions like skin inflammation, inflammatory bowel disease, and chronic pain.✨ Reduces Pro-Inflammatory Cytokines. By inhibiting cytokines like TNF-Alpha, SOD 3 can help soothe inflammation at its source.✨ Supports Healthy Joints a…

PURSER WELLNESSWild genetic facts I learned this week that could actually be deadlyA conversation with Dr. Purser

…ay about the patient, but he had significant cardiovascular disease, which was surprising. I've seen several cases like this um over the years obviously because of homoyine, but um he had interesting findings. He had a um a double homozygou…