THE PURSER WELLNESS ENCYCLOPEDIA
12 resources for your curiosity
What’s searchable?…MTR/MTRR, BHMT, AHCY, CBS, and SUOX. Folate and B12 support remethylation; choline can provide betaine for the BHMT route. Transsulfuration connects homocysteine with cysteine and glutathione, and sulfur compounds pass through additional st…
…-methyltetrahydrofolate, a folate form used in homocysteine remethylation. B12-dependent MTR is another part of that route. Follow the pathway Dr. Purser connects homocysteine with immune signaling, oxidative stress, and antioxidant defens…
…so called: Folate Hydrolase 1 Folate handling begins before remethylation Dr. Purser’s genetic chapters include FOLH1 in folate handling. The earlier genetics reference explains its role in breaking down polyglutamated food folates into for…
… MTHFR contributes to production of the folate form used in remethylation; MTR and MTRR connect that process to B12. His course asks readers to consider the whole cluster rather than build a plan around C677T or A1298C alone. Putting the pi…
…ism. Also called: Methionine Synthase Reductase Keeping the remethylation system working Dr. Purser teaches MTRR alongside MTR because the pathway depends on maintaining an active B12-dependent enzyme system, not simply consuming a nutrient…
…. Purser’s teaching follows homocysteine in two directions: remethylation toward methionine and transsulfuration toward cysteine-related chemistry. Folate/B12 and MTR/MTRR belong in the first discussion; CBS/CTH and glutathione-building mat…
…fur can move toward cysteine. The recycling route is called remethylation. The route toward cysteine is called transsulfuration. Folate and B12 help with one recycling route. Betaine, which can come from choline, helps with another. CBS an…
…in B9, supports DNA building blocks, cell division, and the remethylation of homocysteine to methionine. A severe deficiency can affect blood-cell production and other body systems. Follow the pathway Dr. Purser connects folate with SLC19A…
…scusses rs2236225 and rs1076991, folate forms, homocysteine remethylation, and the relationship between folate demand and choline. Choline can also support the betaine/BHMT route and phosphatidylcholine production. Bring these questions to…
…homocysteine as a junction in sulfur-amino-acid metabolism. Remethylation returns it toward methionine, while transsulfuration moves it toward cysteine. Folate and B12 appear in the recycling discussion; B6 appears in the transsulfuration d…
…m together is useful: methionine/protein supply, folate/B12 remethylation, B6-dependent transsulfuration and riboflavin-related cofactor support are different parts of the pathway. A single low value cannot identify which step is limiting. …
…t of a gene finding. Pathway names describe different jobs Remethylation and transsulfuration are connected, but they are not the same process. Dr. Purser discusses MTHFR alongside CBS, MTR, MTRR and SHMT1 because these genes participate i…
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