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Supports DNA synthesis and one-carbon metabolism, including the pathway that processes homocysteine.
Also called: Vitamin B9 (Folate), Folate, B9, folic acid, methylfolate, 5-MTHF, folinic acid, foods high in folate
Different folate forms, …
The older Purser genetics reference uses the heading “DAOA (AOC1)” in its gut section.
Also called: D-Amino Acid Oxidase Activator
Two similar names, two different pathways
You may see DAOA and AOC1 written together in older materials, but …
ESR1 encodes estrogen receptor alpha, which helps cells respond to estrogen. Receptor signaling is different from the amount of estrogen measured in blood.
FOLR1 encodes folate receptor alpha, which helps cells take up folate and has an important role in folate transport at the brain’s barriers. Blood folate and folate availability in the nervous system are not identical measurements.
MAOB encodes monoamine oxidase B, an enzyme involved in breaking down monoamine compounds, including dopamine. It does not simply build dopamine, and a DNA marker is not a neurotransmitter measurement.
CCL2 encodes MCP-1, a chemokine that attracts monocytes toward sites of immune activity. Recruitment is a different task from the cytokines that activate those cells once they arrive.
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