Explore the p19 and p40 subunits, interleukin-23, and the difference between the IL23A gene and the IL23R receptor.
Understand the connection
IL23A encodes the p19 subunit of IL-23. Together with the p40 subunit from IL12B, it forms the IL…
…hat receives the IL-23 signal. This pathway helps support Th17 immune cells and their downstream cytokines, including IL-17.
Follow the pathway
Dr. Purser connects IL-23 receptor signaling with inflammatory bowel disease, psoriasis, and in…
Explore rs2910397, rs2637125, steroid sulfation, DHEA, DHEAS, bile acids, and hormone and liver pathways.
Understand the connection
SULT2A1 helps sulfate steroids such as DHEA and also participates in the processing of bile acids and other…
…ct should be viewed as a treatment or cure for inflammatory disease.
But supporting cellular health and antioxidant defenses may be an important part of a broader wellness strategy.
Stop thinking only about the symptom.
Start asking wha…
…inction between localized skin findings and more widespread disease.
Bring these questions to your visit
Ask whether the skin findings need a biopsy and what the likely benefits and risks of treatment are. Do not infer a systemic immune di…
…e the NLRP3 sensor, inflammasome priming and activation, IL-1 beta, IL-18, and pyroptosis.
Understand the connection
NLRP3 is an intracellular danger sensor, rather than a circulating cytokine. It can assemble an inflammasome, a protein co…
Explore IL-23, IL-17, TNF-alpha, HLA-B27, spinal inflammation, and treatment questions.
Understand the connection
Ankylosing spondylitis is an inflammatory condition that often affects the spine and sacroiliac joints. Stiffness, pain, and …
… Copper Bound to Ceruloplasmin NCC % = NCC ÷ Total Copper × 100 This calculator is for educational and clinical workflow support only. It does not diagnose, treat, or replace interpretation by a qualified clinician. Results Reference ranges…
…circulating in your bloodstream at one moment in time. Page 1: The Cellular Micronutrient Assay This is the primary page we dive deep into during your consultation. It breaks down approximately 50 key nutrients , including: • Vitamins • Min…
…hione.
Why does this matter? Because CF isn’t just a mucus disease — it’s an inflammatory cytokine storm driven by IL-8, IL-4, IL-5, and IL-13.
Our research shows that restoring glutathione levels can calm these cytokines, reduce inflammat…
…ctually raises levels inside your cells.
Benefits include:
1. Stronger immunity – supports your body’s defense system at the cellular level
2. Lower inflammation – calms harmful cytokines like IL-8 and MCP-1
3. Detox support – helps clear …
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