CCL3
Some search terms matchedCCL3 encodes MIP-1 alpha, a chemokine involved in attracting and activating immune cells. It is related to CCL4, or MIP-1 beta, but the two genes and proteins are distinct.
Also called:
MIP-1 alpha and the chemokine cluster
CCL3 encodes MI…
CCL4
Some search terms matchedCCL4 encodes MIP-1 beta, a chemokine involved in attracting immune cells. It participates in a recruitment network that includes CCL2, CXCL8 and related chemokines.
Also called:
MIP-1 beta and overlapping recruitment signals
CCL4 encodes M…
CCL5
Some search terms matchedCCL5, also called RANTES, is a chemokine that helps direct immune-cell movement. Chemokines tell cells where to go, which is different from measuring the total strength of an immune response.
Also called:
RANTES and immune-cell recruitment…
CD40
Some search terms matchedCD40 encodes a receptor that participates in communication between immune cells, including T-cell help for B-cell responses. Its partner is CD40 ligand, encoded by CD40LG.
Also called:
A conversation between immune cells
CD40 encodes a rec…
CD40LG
Some search terms matchedCD40LG encodes CD40 ligand, which binds CD40 and supports communication needed for effective antibody responses. It is on the X chromosome, which changes how some genetic results must be interpreted.
Also called:
The ligand that helps acti…
CXCL13
Some search terms matchedCXCL13 is a chemokine that attracts cells expressing CXCR5, including B cells. This pairing helps organize immune-cell traffic in lymphoid tissues and some chronic inflammatory settings.
Also called:
Guiding B cells to organized immune sit…
CXCR5
Some search terms matchedCXCR5 encodes the receptor for CXCL13. This receptor helps guide B cells and certain T cells toward locations where organized immune responses develop.
Also called:
Following the CXCL13 signal
CXCR5 encodes the receptor for CXCL13. This re…
DDAH1
Some search terms matchedDDAH1 encodes an enzyme that breaks down asymmetric dimethylarginine, or ADMA. ADMA inhibits nitric oxide synthase; DDAH1 is part of its clearance system, not the inhibitor itself.
Also called:
Clearing ADMA helps preserve nitric oxide sig…
F5
Some search terms matchedF5 encodes coagulation factor V. The well-characterized Factor V Leiden variant, rs6025, can make factor V less responsive to an anticoagulant control mechanism, increasing susceptibility to venous clots. It does not mean the body cannot ma…
F9
Some search terms matchedF9 encodes coagulation factor IX. Disease-causing variants can result in hemophilia B, an inherited bleeding disorder, but a panel marker is not equivalent to a confirmed disease-causing finding.
Also called:
Factor IX and the bleeding sid…
IFNG
Some search terms matchedIFNG encodes interferon gamma, a cytokine involved in cellular immune defense and activation of macrophages. It differs from the Th2 signals more often emphasized in allergic responses.
Also called:
Interferon gamma and macrophage activati…
IL10
Some search terms matchedIL10 encodes interleukin-10, a cytokine that can limit inflammatory responses and help prevent excessive immune-mediated tissue damage. Immune balance includes resolving a response as well as starting one.
Also called:
The immune system al…
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