THE PURSER WELLNESS ENCYCLOPEDIA

Let’s explore “Raynaud’s phenomenon and inflammation”

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Gene referenceSep 23, 2026

PSEN1

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PSEN1 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.

Gene referenceSep 23, 2026

PSEN2

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PSEN2 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.

Gene referenceSep 23, 2026

TNF

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TNF encodes tumor necrosis factor, an immune-signaling protein involved in inflammation, host defense and regulation of cell survival. Its name should not be read as proof that a TNF result indicates cancer.

Gene referenceSep 23, 2026

CCL11

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CCL11 encodes eotaxin-1, a chemokine best known for attracting eosinophils. Its receptor relationships connect it to allergic inflammation as well as broader research into immune signaling.

Gene referenceSep 23, 2026

TGFB1

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TGFB1 encodes transforming growth factor beta 1, which has roles in immune regulation, tissue repair and extracellular-matrix production. Its effects can include both regulation of inflammation and promotion of fibrosis.

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