…y connections
Serine connects with both sulfur handling and folate chemistry. It comes up when discussing the route from homocysteine toward cysteine and the SHMT1 step that involves serine, glycine, and folate. Your nutrient results matter…
…Putting the pieces together
Riboflavin helps make a form of folate the body uses. Your intake and current nutrient status may matter, but an MTHFR result does not prove a riboflavin deficiency or tell you a dose. Include any B-complex or mu…
…s involved in methylation, which is more than a question of folate intake. Rare inherited AHCY deficiency is different from most common variants. Seeing AHCY on a report does not prove that SAH is building up or that you have a rare disorde…
…rker read in isolation.
Also called: Apolipoprotein E
Lipid transport and brain-health risk
APOE encodes a protein that carries lipids between cells. The familiar APOE e2, e3 and e4 groupings depend on the combination of rs429358 and rs7412…
…ether
The teaching links the gut story with IL23R, PEMT and folate-related pathways: immune signaling, membranes/bile and nutrient handling can all enter the same conversation. Those connections do not make an IBS label, Crohn’s disease or …
…ether
The teaching links the gut story with IL23R, PEMT and folate-related pathways: immune signaling, membranes/bile and nutrient handling can all enter the same conversation. Those connections do not make an IBS label, Crohn’s disease or …
… why a methylation discussion should include B12 as well as folate, and why adding more folate alone does not answer every question.
Putting the pieces together
MTRR helps keep the MTR enzyme working. Your B12 status and how you tolerate di…
… attention now, and are several products duplicating B12 or folate?
Reading your own results
Bring your original report, current results, health history, and medicines to your visit. This information can help you ask questions, but it canno…
…’s homocysteine and methylation map because it concerns the transport of B12. The teaching distinction is between eating or supplementing a vitamin, transporting it, and using it in an enzyme reaction.
Putting the pieces together
TCN2 conne…
…ion. The route toward cysteine is called transsulfuration.
Folate and B12 help with one recycling route. Betaine, which can come from choline, helps with another. CBS and CTH carry out the two core steps toward cysteine. These nutrients an…
…bsorption, Intrinsic factor receptor activity, Methylation, Folate metabolism. These are topics to explore, not a diagnosis or a measurement of how the pathway works in your body.
Understanding a result
A gene name is only a starting point.…
… level is not just about what you eat.
Nutrition matters.
Folate matters.
Vitamin B12 matters.
Vitamin B6 matters.
Lifestyle matters.
Genetics may matter too.
So why are we waiting until disease appears before asking what our biology…
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