AOC1
Some search terms matched…d are we evaluating histamine clearance, allergy, mast-cell disease or another digestive problem?
Reading your own results
Bring your original report, current results, health history, and medicines to your visit. This information can help y…
APOE
Some search terms matched…ate-onset Alzheimer’s teaching. This is a reason to discuss cardiovascular and brain health together: blood pressure, lipids, glucose, sleep and family history add information that a genotype cannot supply. APOE risk is probabilistic and do…
ATG16L1
Some search terms matched…sation. Those connections do not make an IBS label, Crohn’s disease or another diagnosis interchangeable, and a common variant is not a substitute for a digestive workup.
A question to bring to your visit
Which part of my history points to …
CD14
Some search terms matched…cteria are present in the blood or establish heart or liver disease.
A question to bring to your visit
What current findings suggest immune activation, and have its possible triggers been assessed?
Variant IDs in the teaching reference: rs2…
FUT2
Some search terms matched…sation. Those connections do not make an IBS label, Crohn’s disease or another diagnosis interchangeable, and a common variant is not a substitute for a digestive workup.
A question to bring to your visit
Which part of my history points to …
HLA-DQA1
Some search terms matched…a marker such as rs2187668 does not establish active celiac disease. Symptoms, appropriate testing and whether gluten is being eaten at the time of evaluation matter.
A question to bring to your visit
Do I have a clinically interpreted HLA …
IL21
Some search terms matched…1 defect. A risk association cannot establish active celiac disease or another autoimmune diagnosis.
A question to bring to your visit
Is the result a regional research marker or a finding with a specific clinical interpretation?
Variant ID…
IL23R
Some search terms matched…ogether
Dr. Purser includes IL23R in his inflammatory bowel disease and psoriasis teaching. The gene, the cytokine IL-23 and the downstream cytokine IL-17A are related but distinct. An inherited marker does not measure receptor function in …
IL6
Some search terms matched…measured IL-6 concentration and a diagnosis of inflammatory disease are three different kinds of information. IL6R adds the receptor side of the story.
More from the teaching: Inflammation, energy and metabolic overlap
In Dr. Purser’s cours…
MMP3
Some search terms matched…lp distinguish mechanical problems from active inflammatory disease. A panel SNP cannot tell you that MMP3 is absent or diagnose arthritis or cancer.
A question to bring to your visit
Is my joint problem primarily mechanical, inflammatory o…
PTGS2
Some search terms matched…ail. Medication choice should consider the actual response, cardiovascular and kidney risks, gastrointestinal history and other medicines.
A question to bring to your visit
What has my actual response to anti-inflammatory treatment been, an…
TNF
Some search terms matched…proach does not replace evaluation of infection, autoimmune disease or another cause of inflammation, and the genotype does not determine a measured TNF level.
More from the teaching: Understanding inflammatory amplification
Dr. Purser disc…
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