THE PURSER WELLNESS ENCYCLOPEDIA

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Gene referenceSep 23, 2026

MTR

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Makes the methionine synthase enzyme, which uses vitamin B12 in the conversion of homocysteine to methionine. Also called: Methionine Synthase The B12-dependent step In Dr. Purser’s teaching map, MTR is the B12-dependent step that converts …

Gene referenceSep 23, 2026

MTRR

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…s maintain the activity of methionine synthase, connecting B12-related chemistry with homocysteine metabolism. Also called: Methionine Synthase Reductase Keeping the remethylation system working Dr. Purser teaches MTRR alongside MTR because…

Gene referenceSep 23, 2026

NAT2

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NAT2 encodes N-acetyltransferase 2, which helps process certain drugs and other compounds. Combinations of variants can influence acetylation status; one SNP usually does not tell the entire story. Also called: N-Acetyltransferase 2 Acetyla…

Gene referenceSep 23, 2026

NOS3

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NOS3 encodes endothelial nitric oxide synthase, which helps blood vessels generate nitric oxide, a signal involved in vascular relaxation. This pathway is distinct from a blood pressure measurement or a diagnosis of vascular disease. Also c…

Gene referenceSep 23, 2026

NR3C2

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NR3C2 encodes the mineralocorticoid receptor, which responds to hormones such as aldosterone and helps regulate salt and fluid balance. It is distinct from the NR3C1 glucocorticoid receptor. Also called: Mineralocorticoid Receptor / Nuclear…

Gene referenceSep 23, 2026

NTRK2

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NTRK2 encodes TrkB, a receptor involved in responding to neurotrophic signals such as BDNF. These signals support nervous-system function and plasticity. NTRK2 is not a phosphatidylserine absorption transporter. Also called: Neurotrophic Re…

Gene referenceSep 23, 2026

PEMT

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Makes an enzyme involved in producing phosphatidylcholine, a component of cell membranes. Genetic findings alone do not establish a choline deficiency. Also called: Phosphatidylethanolamine N-Methyltransferase, choline, phosphatidylcholine …

Gene referenceSep 23, 2026

PSEN2

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PSEN2 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis. Also called:…

Gene referenceSep 23, 2026

PTGS2

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PTGS2, commonly called COX-2, encodes an enzyme involved in prostaglandin production. Prostaglandins participate in pain, fever and inflammatory signaling. Also called: COX2, Cyclooxygenase 2 COX-2 and inflammatory prostaglandins PTGS2, com…

Gene referenceSep 23, 2026

SOD2

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SOD2 works in mitochondria as part of the body’s antioxidant defenses. Also called: Superoxide Dismutase 2 Superoxide defense in its own setting Dr. Purser teaches SOD as one member of an antioxidant team. SOD2 works in mitochondria and use…

Gene referenceSep 23, 2026

SOD3

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SOD3 works outside cells as part of the body’s antioxidant defenses. Also called: Superoxide Dismutase 3 Superoxide defense in its own setting Dr. Purser teaches SOD as one member of an antioxidant team. SOD3 works outside cells and uses co…

Gene referenceSep 23, 2026

TCN2

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TCN2 helps carry vitamin B12 in the body. A gene result alone cannot tell you your B12 status. Also called: Transcobalamin II B12 must be carried as well as consumed TCN2 appears in Dr. Purser’s homocysteine and methylation map because it c…

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