THE PURSER WELLNESS ENCYCLOPEDIA

Let’s explore “Hirschsprung’s disease & genetics”

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Gene referenceSep 23, 2026

GSTP1

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GSTP1 helps your body use glutathione to process some compounds. Also called: Glutathione S-Transferase Pi 1 Using glutathione in conjugation GSTP1 belongs to the glutathione transferase family. These enzymes use glutathione in conjugation …

Gene referenceSep 23, 2026

GSTT1

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GSTT1 helps your body use glutathione to process some compounds. Also called: Glutathione S-Transferase Theta 1, GSTT Using glutathione in conjugation GSTT1 belongs to the glutathione transferase family. These enzymes use glutathione in con…

Gene referenceSep 23, 2026

HLA-DQA1

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HLA-DQA1 contributes to an HLA-DQ protein that presents antigen fragments to CD4 T cells. HLA-DQ function depends on pairing with an HLA-DQB chain, so an isolated marker is not a complete HLA type. Also called: HLADQA1, Human Leukocyte Anti…

Gene referenceSep 23, 2026

HLA-DQA2

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HLA-DQA2 is part of the HLA class II region involved in immune recognition. It should not be treated as interchangeable with HLA-DQA1 or as a measurement of how well the immune system fights infections. Also called: HLADQA2, Human Leukocyte…

Gene referenceSep 23, 2026

MAOA

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MAOA helps break down some chemical messengers. A gene result cannot predict a mood or behavior. Also called: MAO-A, Monoamine Oxidase A Neurotransmitter breakdown in context Dr. Purser places MAOA in the neurotransmitter-breakdown part of …

Gene referenceSep 23, 2026

MMP3

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MMP3 encodes matrix metalloproteinase 3, an enzyme involved in breaking down components of the extracellular matrix. Controlled remodeling is part of repair, while excess activity can accompany inflammatory tissue damage. Also called: Matri…

Gene referenceSep 23, 2026

MTR

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Makes the methionine synthase enzyme, which uses vitamin B12 in the conversion of homocysteine to methionine. Also called: Methionine Synthase The B12-dependent step In Dr. Purser’s teaching map, MTR is the B12-dependent step that converts …

Gene referenceSep 23, 2026

NAT2

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NAT2 encodes N-acetyltransferase 2, which helps process certain drugs and other compounds. Combinations of variants can influence acetylation status; one SNP usually does not tell the entire story. Also called: N-Acetyltransferase 2 Acetyla…

Gene referenceSep 23, 2026

NTRK2

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NTRK2 encodes TrkB, a receptor involved in responding to neurotrophic signals such as BDNF. These signals support nervous-system function and plasticity. NTRK2 is not a phosphatidylserine absorption transporter. Also called: Neurotrophic Re…

Gene referenceSep 23, 2026

PEMT

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Makes an enzyme involved in producing phosphatidylcholine, a component of cell membranes. Genetic findings alone do not establish a choline deficiency. Also called: Phosphatidylethanolamine N-Methyltransferase, choline, phosphatidylcholine …

Gene referenceSep 23, 2026

TCN2

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TCN2 helps carry vitamin B12 in the body. A gene result alone cannot tell you your B12 status. Also called: Transcobalamin II B12 must be carried as well as consumed TCN2 appears in Dr. Purser’s homocysteine and methylation map because it c…

Gene referenceSep 23, 2026

TNF

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TNF encodes tumor necrosis factor, an immune-signaling protein involved in inflammation, host defense and regulation of cell survival. Its name should not be read as proof that a TNF result indicates cancer. Also called: Tumor Necrosis Fact…

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