Let’s explore “folate”

What is the MTHFR SNP? It’s the genes transcription error that causes to process folate poorly, making you SUPER tired. You’re not making ATP, the energy currency of our cells, at the rate you could be. You need the right supplementation to

Folate deficiency- causes some nasty symptoms, but where does it really come from? Both MTHFR and FOLR2 genes handle the folate pathways and any genetic errors on those genes can really mess you up.

PURSER WELLNESSWhat Causes Chronic Fatigue Syndrome?A conversation with Dr. Purser

Do you know what causes chronic fatigue? Dr. Purser explains the top causes of Chronic Fatigue Syndrome (CFS) and shares what steps to take to feel normal again. Discover why CFS is a symptom of underlying conditions and what the treatment of underlying causes of CFS includes. Dr. Purser dispels the myth of medication deficiency related to CFS symptoms. Discover the relationship of nutritional deficiencies, hormone imbalance, and poorly understood genetic causes from MTHFR deficiency to fatigue. Learn what contributes to fatigue when the absorption of Vitamin B12, folate, pantothenate, and oth

The folate cycle, methionine cycle, and transsulfuration pathway work together to move methyl groups and process homocysteine.

Explore folate, B12, B6, and homocysteine in a bone-health discussion.

Follow Dr. Purser’s discussion of folate metabolism and inflammation.

Everyone talks about MTHFR. But what if that is only one piece of the puzzle? MTHFR helps process folate, while MTR helps recycle homocysteine back into methionine with the help of vitamin B12. Two genes. Different roles. One interco

BHMT helps recycle homocysteine into methionine using betaine. It is a different route from the folate and B12 pathway.

DHFR helps reduce folic acid and dihydrofolate to tetrahydrofolate-related forms used in cellular metabolism. This is one part of the folate system, distinct from MTHFR and folate transport into cells.

FOLH1 helps break down folate from food so it can be absorbed. This is different from the MTHFR step.

FOLR1 encodes folate receptor alpha, which helps cells take up folate and has an important role in folate transport at the brain’s barriers. Blood folate and folate availability in the nervous system are not identical measurements.

FOLR2 encodes folate receptor beta, a folate-binding protein expressed in particular cell types, including subsets of immune cells. It is distinct from the FOLR1 receptor and the SLC19A1 reduced folate carrier.